

STUDIES
PREMIUM ORGANIC
BACKED BY RESEARCH, PROVEN BY RESULTS
STUDIES
STUDIES WITH AHE
Backed by Research, Proven by Results
At PREMIUM ORGANIC, innovation and efficacy go hand in hand. With over 12 clinical studies, 70 preclinical studies, and numerous consumer studies we have established ALPIN HEILMOOR EXTRACT™ (AHE) as a multifunctional active ingredient backed by science. Our research spans across skin, hair, and oral care, ensuring proven results for modern personal care formulations.

12
CLINICAL STUDIES
70
PRECLINICAL STUDIES

SKIN CARE

STUDIES
SKIN CARE
Study Highlights SKIN:
Comprehensive Research Across Key Areas
AGING
STUDIES with a MASK
CLINICALLY PROVEN IMMEDIATE RESULTS IN JUST 15 MINUTES
RINSE-OFF
IMMEDIATE
THE STUDY:
The benefits of ALPIN HEILMOOR EXTRACT™ were evaluated by assessing hydration levels and crow’s feet surface 15 minutes after a single application of a mask containing 1.5% of the active ingredient.

THE RESULTS:
ALPIN HEILMOOR EXTRACT™ (1.5%) significantly improves skin’s appearance in just 15 minutes.
-9.4%
Reduction in crow’s feet wrinkles
+16.0%
Improvement in skin hydration

BEFORE
AFTER
+16.0%
Improvement in skin hydration
RINSE-OFF
IMMEDIATE
-9.4%
Reduction in crow's feet wrinkles
RINSE-OFF
IMMEDIATE
BEFORE
AFTER
AGING
STUDIES with a CREAM
PROVEN EFFICACY AFTER 28 DAYS OF USE
LEAVE-ON
LONG-TERM

THE STUDY:
The benefits of a cream containing 1.5% ALPIN HEILMOOR EXTRACT™ (AHE) were evaluated over 28 days in a clinical study involving twice-daily use, assessing improvements in skin complexion, firmness, elasticity, and hydration.

THE RESULTS:
The cream demonstrated significant long-term benefits, including:
+17.0%
Improvement in complexion (eye skin radiance and reduced facial fatigue)
+12.0%
Increase in elasticity
+6.0%
Long-term moisturization
BEFORE
AFTER
+17%
Improvement of skin complexion and eye skin radiance
LEAVE-ON
LONG-TERM
ACNE-PRONE SKIN
STUDIES with a CLEANSING
CLINICALLY PROVEN RESULTS AFTER 21 DAYS OF USE
RINSE-OFF
LONG-TERM
THE STUDY:
The benefits of a rinse-off cleansing gel containing 1.5% ALPIN HEILMOOR EXTRACT™ (AHE) were evaluated in a clinical study conducted over 21 days with twice-daily use. The study assessed its impact on open comedones, papules, and the product’s comedogenic potential.


THE RESULTS:
The cleansing gel demonstrated significant improvements for acne-prone skin:
-19.0%
Reduction in open comedones
-24.0%
Reduction in papules
-22.0%
Reduction in sebum production
NO COMEDOGENIC POTENTIAL
Additionally, the study confirmed that the product showed no comedogenic potential, ensuring its suitability for sensitive and acne-prone skin.
-24.0%
Reduction in papules
RINSE-OFF
LONG-TERM
BEFORE
AFTER
ACNE-PRONE SKIN
STUDIES with a CREAM
CLINICALLY PROVEN RESULTS AFTER 28 DAYS OF USE
LEAVE-ON
LONG-TERM
THE STUDY:
The benefits of a leave-on cream containing 1.5% ALPIN HEILMOOR EXTRACT™ (AHE) were evaluated in a clinical study conducted over 28 days with twice-daily use. The study focused on its effects on inflammatory and non-inflammatory acne lesions, including microcysts, papules, and pustules, as well as its comedogenic potential.

THE RESULTS:
The cream demonstrated remarkable efficacy for acne-prone skin:
-34.0%
Reduction in microcysts (non-inflammatory lesions)
-46.0%
Reduction in papules
-42.0%
Reduction in pustules
-33.0%
Reduction in total lesions

NO COMEDOGENIC POTENTIAL
The study further confirmed that the cream had no comedogenic potential, making it safe and effective for long-term use on acne-prone skin.
BEFORE
AFTER
-46.0%
Reduction in papules
LEAVE-ON
LONG-TERM
SENSITIVE SKIN
STUDIES with a CLEANSING GEL
CLINICALLY PROVEN IMMEDIATE RELIEF IN JUST 10 MINUTES
RINSE-OFF
IMMEDIATE
THE STUDY:
The benefits of a rinse-off cleansing gel containing 1.5% ALPIN HEILMOOR EXTRACT™ (AHE) were evaluated in a clinical study after a single application. The study measured the reduction in stinging intensity and improvement of cutaneous reactivity on the nasolabial region, following capsaicin-induced sensitivity.

THE RESULTS:
The cleansing gel demonstrated immediate soothing effects:
-33.0%
Reduction in stinging intensity after 1 minute.
-42.0%
Reduction in stinging intensity after 10 minutes.

BEFORE
AFTER
-42.0%
Reduction in stinging after just 10 minutes
RINSE-OFF
IMMEDIATE
SENSITIVE SKIN
STUDIES with a CREAM
CLINICALLY PROVEN IMMEDIATE RELIEF IN JUST 3 MINUTES
LEAVE-ON
IMMEDIATE
THE STUDY:
The benefits of a leave-on cream containing 2.5% ALPIN HEILMOOR EXTRACT™ (AHE) were evaluated after a single application. The study measured the reduction in stinging intensity and the improvement in cutaneous reactivity on the nasolabial region, following capsaicin-induced sensitivity.


THE RESULTS:
The leave-on cream showed significant instant soothing effects:
-50.0%
Reduction in stinging intensity after 30 seconds
-70.0%
Reduction in stinging intensity after 3 minutes.
-70.0%
Reduction in stinging intensity (immediate)
LEAVE-ON
IMMEDIATE
BEFORE
AFTER
SENSITIVE SKIN
STUDIES with a CREAM
CLINICALLY PROVEN SOOTHING EFFECTS AFTER 28 DAYS
LEAVE-ON
LONG-TERM

THE STUDY:
The benefits of a leave-on cream containing 2.5% ALPIN HEILMOOR EXTRACT™ (AHE) were evaluated in a clinical study over 28 days of twice-daily use. The study assessed the cream’s ability to provide preventive soothing effects by measuring the reduction in stinging intensity and improvement in global skin reactivity levels after lactic acid-induced sensitivity.

THE RESULTS:
The leave-on cream showed significant instant soothing effects:
-67.0%
Reduction in stinging intensity after 28 days
BEFORE
AFTER
-67.0%
Reduction in stinging intensity (preventive)
LEAVE-ON
LONG-TERM
HAIR CARE

STUDIES
HAIR CARE
TRANSFORMATIVE BENEFITS FOR HAIR AND SCALP CARE
ALPIN HEILMOOR EXTRACT™ (AHE) is a proven, multifunctional active ingredient that delivers measurable results in both hair care and scalp care. Its unique bioactive properties enhance hair texture, strength, and elasticity, while revitalizing and hydrating the scalp for improved overall health.
Explore the Key Study Highlights in Hair and Scalp Care!
BLEACHED HAIR
STUDIES with a HAIR MASK
CLINICALLY PROVEN EFFECTS AFTER SINGLE APPLICATION
RINSE-OFF
IMMEDIATE
THE STUDY:
The benefits of a hair mask containing 5.0% ALPIN HEILMOOR EXTRACT™ (AHE) were evaluated after a single application. The study assessed fibre flexibility and elasticity in 25 bleached hair strands using Tensile Strength and Young’s modulus.


THE RESULTS:
The hair mask showed significant improvements:
+8.6%
Improvement in fibre flexibility
Enhanced elasticity through reduced Tensile Strength and Young’s modulus
WHITE HAIR
STUDIES with a HAIR MASK
CLINICALLY PROVEN EFFECTS AFTER SINGLE APPLICATION
RINSE-OFF
IMMEDIATE
THE STUDY:
The benefits of a hair mask containing 5.0% ALPIN HEILMOOR EXTRACT™ (AHE) were evaluated after a single application. The study focused on fibre flexibility and elasticity in 25 white hair strands using Tensile Strength and Young’s modulus.

THE RESULTS:
The hair mask delivered the following benefits:
+11.2%
Improvement in fibre flexibility
Enhanced elasticity through reduced Tensile Strength and Young’s modulus

DYED or COLORED HAIR
STUDIES with a SHAMPOO and CONDITIONER
CLINICALLY PROVEN RESULTS FOR RESTORING HAIR STRENGTH, SHINE, AND MANAGEABILITY AFTER 28 DAYS OF USE
RINSE-OFF
LONG-TERM

THE STUDY:
The benefits of a shampoo containing 0.3% ALPIN HEILMOOR EXTRACT™ (AHE) were evaluated in a clinical study over 28 days of regular use. The study assessed improvements in hair softness, strength, and structure, as well as scalp revitalization.

NO COMEDOGENIC POTENTIAL
THE RESULTS:
The shampoo showed significant improvements:
+10.0%
Increase in hair softness and strength
+5.0%
Improvement in scalp hydration and revitalization
+5.0%
Enhanced manageability with detangling and reduced flyaways

THE STUDY:
The benefits of a conditioner containing 0.3% ALPIN HEILMOOR EXTRACT™ (AHE) were evaluated in a clinical study over 28 days of regular use. The study focused on improvements in hair texture, shine, and manageability.

THE RESULTS:
The conditioner delivered the following benefits:
+10.0%
Improvement in hair strength and detangling
+5.0%
Increase in shine and volume
+10.0%
Enhanced styling ease and overall manageability
ORAL CARE

STUDIES
ORAL CARE
OUR CLINICAL STUDIES IN THE ORAL CARE FIELD COVER:
WHITENING EFFECT
PLAQUE REDUCTION
GINGIVAL HEALTH
ANTI-BACTERIAL ACTION
ORAL CARE
STUDIES with a TOOTHPASTE
CLINICALLY PROVEN ORAL EFFECTS AFTER 28 DAYS

LONG-TERM
The toothpaste demonstrated significant efficacy across multiple areas of oral care:
THE STUDY:
The benefits of a toothpaste containing 5.0% ALPIN HEILMOOR EXTRACT™ (AHE) were evaluated in a clinical-dermatological and dental study over 28 days of twice-daily use. The study assessed improvements in key oral health parameters, including tooth shade, plaque, gingival health, and microbial balance.


WHITENING EFFECT
THE RESULTS:
+21.0%
Improvement of tooth shade

PLAQUE REDUCTION
THE RESULTS:
-75.0%
Reduction of Plaque

GINGIVAL HEALTH
THE RESULTS:
-77.0%
Reduction in gingival inflammation
-82.0%
Reduction in gingival bleeding

ANTIMICROBIAL ACTION
THE RESULTS:
-99.0%
Reduction of P. gingivitis ...
and significant reduction of five other key oral pathogens, including
T. forsythia, and A. actinomycetemcomitans, which are linked to gingival imbalance.
BEFORE
AFTER
COLOURED PLAQUE
-75%
Reduction of Plaque
PRECLINICAL STUDIES
Understanding the MECHANISM of ACTION
OF OUR PLATFORM TECHNOLOGY
MECHANISM of ACTION
Our preclinical studies have demonstrated the diverse biological effects of ALPIN HEILMOOR EXTRACT™ (AHE), validating its multifunctionality across skin, scalp, and oral health applications, as well as its potential for nutraceuticals and internal well-being.
THE FINDINGS HIGHLIGHT AHE'S ABILITY TO:

MICROBIAL MODULATION
Supports a balanced microbiome by promoting beneficial bacteria (e.g., Staphylococcus epidermidis) while inhibiting harmful pathogens like P. gingivalis and Staphylococcus aureus.

BARRIER FUNCTION, CELLULAR HEALTH & LIPID METABOLISM
Enhances skin integrity through keratinocyte modulation (K10 upregulation, K16 downregulation), strengthens cell adhesion (E-Cadherin B1 & B2), and contributes to sphingolipid metabolism, crucial for skin barrier function and cellular signaling.

ANTI-INFLAMMATORY & IMMUNMODULATION
Suppresses key inflammatory markers (IL-6, IL-8, TNF-α, IL-1β), helping to regulate immune responses and support skin homeostasis.

ANTIOXIDANT PROTECTION & CELLULAR DEFENSE
Reduces oxidative stress by inhibiting reactive oxygen species (ROS) and regulating nitric oxide, which helps combat premature aging and environmental damage.

CELLULAR RENEWAL, WOUND HEALING & TISSUE REGENERATION
Reduces senescent cell populations to promote longevity and repair, enhances tissue regeneration, and accelerates the healing process.