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STUDIES

PREMIUM ORGANIC

BACKED BY RESEARCH, PROVEN BY RESULTS 

STUDIES

STUDIES WITH AHE

Backed by Research, Proven by Results

At PREMIUM ORGANIC, innovation and efficacy go hand in hand. With over 12 clinical studies, 70 preclinical studies, and numerous consumer studies we have established ALPIN HEILMOOR EXTRACT™ (AHE) as a multifunctional active ingredient backed by science. Our research spans across skin, hair, and oral care, ensuring proven results for modern personal care formulations.

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12

CLINICAL STUDIES

70

PRECLINICAL STUDIES

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OUR CLINICAL STUDIES SPAN SKIN, HAIR, AND ORAL CARE.

Let's dive into our clinical research across key applications!

SKIN CARE

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 STUDIES 

SKIN CARE

Study Highlights SKIN:
Comprehensive Research Across Key Areas

AGING

STUDIES with a MASK

CLINICALLY PROVEN IMMEDIATE RESULTS IN JUST 15 MINUTES

RINSE-OFF
IMMEDIATE

THE STUDY:

The benefits of ALPIN HEILMOOR EXTRACT™ were evaluated by assessing hydration levels and crow’s feet surface 15 minutes after a single application of a mask containing 1.5% of the active ingredient.

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THE RESULTS:

ALPIN HEILMOOR EXTRACT™ (1.5%) significantly improves skin’s appearance in just 15 minutes.

-9.4%

Reduction in crow’s feet wrinkles

+16.0%

Improvement in skin hydration

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BEFORE

AFTER

+16.0%

Improvement in skin hydration 

RINSE-OFF
IMMEDIATE

-9.4%

Reduction in crow's feet wrinkles

RINSE-OFF
IMMEDIATE

BEFORE

AFTER

AGING

STUDIES with a CREAM

PROVEN EFFICACY AFTER 28 DAYS OF USE

LEAVE-ON
LONG-TERM

THE STUDY:

The benefits of a cream containing 1.5% ALPIN HEILMOOR EXTRACT™ (AHE) were evaluated over 28 days in a clinical study involving twice-daily use, assessing improvements in skin complexion, firmness, elasticity, and hydration.

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THE RESULTS:

The cream demonstrated significant long-term benefits, including:

+17.0%

Improvement in complexion (eye skin radiance and reduced facial fatigue)

+12.0%

Increase in elasticity

+6.0%

Long-term moisturization

BEFORE

AFTER

+17%

Improvement of skin complexion and eye skin radiance

LEAVE-ON
LONG-TERM

ACNE-PRONE SKIN

STUDIES with a CLEANSING

CLINICALLY PROVEN RESULTS AFTER 21 DAYS OF USE

RINSE-OFF
LONG-TERM

THE STUDY:

The benefits of a rinse-off cleansing gel containing 1.5% ALPIN HEILMOOR EXTRACT™ (AHE) were evaluated in a clinical study conducted over 21 days with twice-daily use. The study assessed its impact on open comedones, papules, and the product’s comedogenic potential.

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THE RESULTS:

The cleansing gel demonstrated significant improvements for acne-prone skin:

-19.0%

Reduction in open comedones

-24.0%

Reduction in papules

-22.0%

Reduction in sebum production

NO COMEDOGENIC POTENTIAL

Additionally, the study confirmed that the product showed no comedogenic potential, ensuring its suitability for sensitive and acne-prone skin.

-24.0%

Reduction in papules

RINSE-OFF
LONG-TERM

BEFORE

AFTER

ACNE-PRONE SKIN

STUDIES with a CREAM

CLINICALLY PROVEN RESULTS AFTER 28 DAYS OF USE

LEAVE-ON
LONG-TERM

THE STUDY:

The benefits of a leave-on cream containing 1.5% ALPIN HEILMOOR EXTRACT™ (AHE) were evaluated in a clinical study conducted over 28 days with twice-daily use. The study focused on its effects on inflammatory and non-inflammatory acne lesions, including microcysts, papules, and pustules, as well as its comedogenic potential.

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THE RESULTS:

The cream demonstrated remarkable efficacy for acne-prone skin:

-34.0%

Reduction in microcysts (non-inflammatory lesions)

-46.0%

Reduction in papules

-42.0%

Reduction in pustules

-33.0%

Reduction in total lesions

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NO COMEDOGENIC POTENTIAL

The study further confirmed that the cream had no comedogenic potential, making it safe and effective for long-term use on acne-prone skin.

BEFORE

AFTER

-46.0%

Reduction in papules

LEAVE-ON
LONG-TERM

SENSITIVE SKIN

STUDIES with a CLEANSING GEL

CLINICALLY PROVEN IMMEDIATE RELIEF IN JUST 10 MINUTES

RINSE-OFF
IMMEDIATE

THE STUDY:

The benefits of a rinse-off cleansing gel containing 1.5% ALPIN HEILMOOR EXTRACT™ (AHE) were evaluated in a clinical study after a single application. The study measured the reduction in stinging intensity and improvement of cutaneous reactivity on the nasolabial region, following capsaicin-induced sensitivity.

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THE RESULTS:

The cleansing gel demonstrated immediate soothing effects:

-33.0%

Reduction in stinging intensity after 1 minute.

-42.0%

Reduction in stinging intensity after 10 minutes.

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BEFORE

AFTER

-42.0%

Reduction in stinging after just 10 minutes

RINSE-OFF
IMMEDIATE

The study confirmed significant instant calming effects, making the cleansing gel ideal for sensitive skin formulations.

SENSITIVE SKIN

STUDIES with a CREAM

CLINICALLY PROVEN IMMEDIATE RELIEF IN JUST 3 MINUTES

LEAVE-ON
IMMEDIATE

THE STUDY:

The benefits of a leave-on cream containing 2.5% ALPIN HEILMOOR EXTRACT™ (AHE) were evaluated after a single application. The study measured the reduction in stinging intensity and the improvement in cutaneous reactivity on the nasolabial region, following capsaicin-induced sensitivity.

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THE RESULTS:

The leave-on cream showed significant instant soothing effects:

-50.0%

Reduction in stinging intensity after 30 seconds

-70.0%

Reduction in stinging intensity after 3 minutes.

-70.0%

Reduction in stinging intensity (immediate)

LEAVE-ON
IMMEDIATE

BEFORE

AFTER

SENSITIVE SKIN

STUDIES with a CREAM

CLINICALLY PROVEN SOOTHING EFFECTS AFTER 28 DAYS

LEAVE-ON
LONG-TERM
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THE STUDY:

The benefits of a leave-on cream containing 2.5% ALPIN HEILMOOR EXTRACT™ (AHE) were evaluated in a clinical study over 28 days of twice-daily use. The study assessed the cream’s ability to provide preventive soothing effects by measuring the reduction in stinging intensity and improvement in global skin reactivity levels after lactic acid-induced sensitivity.

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THE RESULTS:

The leave-on cream showed significant instant soothing effects:

-67.0%

Reduction in stinging intensity after 28 days

BEFORE

AFTER

-67.0%

Reduction in stinging intensity (preventive)

LEAVE-ON
LONG-TERM

ALPIN HEILMOOR EXTRACT™ significantly improves symptoms of stinging, itching, tautness, and scaling, making it an ideal solution for sensitive skin care.

HAIR CARE

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 STUDIES 

HAIR CARE

TRANSFORMATIVE BENEFITS FOR HAIR AND SCALP CARE

ALPIN HEILMOOR EXTRACT™ (AHE) is a proven, multifunctional active ingredient that delivers measurable results in both hair care and scalp care. Its unique bioactive properties enhance hair texture, strength, and elasticity, while revitalizing and hydrating the scalp for improved overall health.

Explore the Key Study Highlights in Hair and Scalp Care!

BLEACHED HAIR

STUDIES with a HAIR MASK

CLINICALLY PROVEN EFFECTS AFTER SINGLE APPLICATION

RINSE-OFF
IMMEDIATE

THE STUDY:

The benefits of a hair mask containing 5.0% ALPIN HEILMOOR EXTRACT™ (AHE) were evaluated after a single application. The study assessed fibre flexibility and elasticity in 25 bleached hair strands using Tensile Strength and Young’s modulus.

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THE RESULTS:

The hair mask showed significant improvements:

+8.6%

Improvement in fibre flexibility

Enhanced elasticity through reduced Tensile Strength and Young’s modulus

WHITE HAIR

STUDIES with a HAIR MASK

CLINICALLY PROVEN EFFECTS AFTER SINGLE APPLICATION

RINSE-OFF
IMMEDIATE

THE STUDY:

The benefits of a hair mask containing 5.0% ALPIN HEILMOOR EXTRACT™ (AHE) were evaluated after a single application. The study focused on fibre flexibility and elasticity in 25 white hair strands using Tensile Strength and Young’s modulus.

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THE RESULTS:

The hair mask delivered the following benefits:

+11.2%

Improvement in fibre flexibility

Enhanced elasticity through reduced Tensile Strength and Young’s modulus

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These results demonstrate AHE’s ability to restore flexibility, elasticity, and vitality in damaged, bleached, or aged white hair.

DYED or COLORED HAIR

STUDIES with a SHAMPOO and CONDITIONER

CLINICALLY PROVEN RESULTS FOR RESTORING HAIR STRENGTH, SHINE, AND MANAGEABILITY AFTER 28 DAYS OF USE

RINSE-OFF
LONG-TERM
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THE STUDY:

The benefits of a shampoo containing 0.3% ALPIN HEILMOOR EXTRACT™ (AHE) were evaluated in a clinical study over 28 days of regular use. The study assessed improvements in hair softness, strength, and structure, as well as scalp revitalization.

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NO COMEDOGENIC POTENTIAL

THE RESULTS:

The shampoo showed significant improvements:

+10.0%

Increase in hair softness and strength

+5.0%

Improvement in scalp hydration and revitalization

+5.0%

Enhanced manageability with detangling and reduced flyaways

Participants rated the shampoo highly for its performance and tolerability.

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THE STUDY:

The benefits of a conditioner containing 0.3% ALPIN HEILMOOR EXTRACT™ (AHE) were evaluated in a clinical study over 28 days of regular use. The study focused on improvements in hair texture, shine, and manageability.

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THE RESULTS:

The conditioner delivered the following benefits:

+10.0%

Improvement in hair strength and detangling

+5.0%

Increase in shine and volume

+10.0%

Enhanced styling ease and overall manageability

Participants consistently appreciated the conditioner for its performance and suitability for dyed or colored hair.

ORAL CARE

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 STUDIES 

ORAL CARE

OUR CLINICAL STUDIES IN THE ORAL CARE FIELD COVER:

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WHITENING EFFECT


PLAQUE REDUCTION


GINGIVAL HEALTH

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ANTI-BACTERIAL ACTION

ORAL CARE

STUDIES with a TOOTHPASTE

CLINICALLY PROVEN ORAL EFFECTS AFTER 28 DAYS

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LONG-TERM

The toothpaste demonstrated significant efficacy across multiple areas of oral care:

THE STUDY:

The benefits of a toothpaste containing 5.0% ALPIN HEILMOOR EXTRACT™ (AHE) were evaluated in a clinical-dermatological and dental study over 28 days of twice-daily use. The study assessed improvements in key oral health parameters, including tooth shade, plaque, gingival health, and microbial balance.

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WHITENING EFFECT

THE RESULTS:

+21.0%

Improvement of tooth shade

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PLAQUE REDUCTION

THE RESULTS:

-75.0%

Reduction of Plaque

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GINGIVAL HEALTH

THE RESULTS:

-77.0%

Reduction in gingival inflammation

-82.0%

Reduction in gingival bleeding

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ANTIMICROBIAL ACTION

THE RESULTS:

-99.0%

Reduction of P. gingivitis ...

and significant reduction of five other key oral pathogens, including

T. forsythia, and A. actinomycetemcomitans, which are linked to gingival imbalance.

BEFORE

AFTER

COLOURED PLAQUE

-75%

Reduction of Plaque

These findings confirm ALPIN HEILMOOR EXTRACT™ as a multifunctional ingredient that addresses key concerns in oral care, delivering clinically proven benefits for whitening, plaque control, gingival health, and antimicrobial action.

PRECLINICAL STUDIES

Understanding the MECHANISM of ACTION

OF OUR PLATFORM TECHNOLOGY

MECHANISM of ACTION

Our preclinical studies have demonstrated the diverse biological effects of ALPIN HEILMOOR EXTRACT™ (AHE), validating its multifunctionality across skin, scalp, and oral health applications, as well as its potential for nutraceuticals and internal well-being.

THE FINDINGS HIGHLIGHT AHE'S ABILITY TO:

 

MICROBIAL MODULATION

Supports a balanced microbiome by promoting beneficial bacteria (e.g., Staphylococcus epidermidis) while inhibiting harmful pathogens like P. gingivalis and Staphylococcus aureus.

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BARRIER FUNCTION, CELLULAR HEALTH & LIPID METABOLISM

Enhances skin integrity through keratinocyte modulation (K10 upregulation, K16 downregulation), strengthens cell adhesion (E-Cadherin B1 & B2), and contributes to sphingolipid metabolism, crucial for skin barrier function and cellular signaling.

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ANTI-INFLAMMATORY & IMMUNMODULATION

Suppresses key inflammatory markers (IL-6, IL-8, TNF-α, IL-1β), helping to regulate immune responses and support skin homeostasis.

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ANTIOXIDANT PROTECTION & CELLULAR DEFENSE

Reduces oxidative stress by inhibiting reactive oxygen species (ROS) and regulating nitric oxide, which helps combat premature aging and environmental damage.

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CELLULAR RENEWAL, WOUND HEALING & TISSUE REGENERATION

Reduces senescent cell populations to promote longevity and repair, enhances tissue regeneration, and accelerates the healing process.

Want to explore how AHE can transform your formulations?

Contact us for full study results and insights into its multifunctional applications!

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